Statistical design for a small serial dilution series
نویسندگان
چکیده
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In a serial dilution assay, the concentration of a compound is estimated by combining measurements of several different dilutions of an unknown sample. The relation between concentration and measurement is nonlinear and heteroscedastic, and so it is not appropriate to weight these measurements equally. In the standard existing approach for analysis of these data, a large proportion of the measu...
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ژورنال
عنوان ژورنال: Statistics in Medicine
سال: 2009
ISSN: 0277-6715
DOI: 10.1002/sim.3774